All of the SSRIs in the study caused a gradual increase in weight. The only SSRI to cause some initial weight loss before weight gain was fluoxetine. Up to 25% of people who take antidepressants gain weight. Long-term use of the following SSRIs may cause weight gain :. If you do gain some weight while taking an antidepressant, the drug may not actually be. No one knows for sure why antidepressants do.
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It would be expected that all SSRIs should exert a similar anorectic action. The past few months I have noticed I am having weight gain.